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Western blot analysis revealed a significant upregulation of P16 and P21 protein levels in the ovaries of the PS-MPs treated group compared to the control group (Fig

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Administered once weekly via subcutaneous injection, starting at 2.5 mg and titrated every 4 weeks to a maintenance dose of 515 mg

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This could indeed imply risk of anhedonia loss of enjoyment in things

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Weight loss : Retatrutide showed 28.7% at 68 weeks (Phase 3 TRIUMPH-4) versus survodutide's 18.7% at 46 weeks (Phase 2), though cross-trial comparisons are inherently limited

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